FAQ

Frequently Asked Questions

What is PepMates Daily?

PepMates Daily is a once-daily supplement formulated for people using GLP-1 medications (semaglutide, tirzepatide, retatrutide) or other peptide protocols who experience anhedonia — emotional flatness, reduced motivation, or diminished joy. It's designed to support the dopamine and mood pathways that GLP-1 drugs can suppress.

Is it safe to take with semaglutide / tirzepatide?

PepMates Daily uses natural botanical ingredients with strong safety profiles. None of the ingredients are contraindicated with GLP-1 medications in the published literature. That said, we always recommend consulting your prescribing physician before adding any supplement to your protocol.

When will I notice a difference?

Most customers report noticing improvements in mood and motivation within 2–4 weeks of consistent daily use. The Affron® saffron extract in our formula has RCT data showing measurable effects at week 4. Give it a full 30 days before evaluating.

How do I take it?

Take 3 capsules with your largest meal of the day. Consistent daily use is more important than timing.

Do you offer a subscription?

Yes — Subscribe & Save gets you 20% off every order, shipped automatically on your schedule. You can pause, skip, or cancel anytime from your account.

What's your return policy?

We offer a 30-day money-back guarantee. If you're not satisfied after a full month of daily use, contact us for a full refund — no questions asked.